Inhibition of insulin-regulated aminopeptidase (IRAP) by arylsulfonamides
In particular, [1- 13 C]DHA, a 13 C enriched version of dehydroascorbic acid, has been studied with hyperpolarized (HP) 13 C magnetic resonance (MR) in preclinical models of cancer, diabetes, acute kidney injury, and fatty liver disease 15,16,17,18,19,20
The shape of the curve was as expected for an enzyme-catalysed reaction showing that saturation of the enzyme reaction occurred at higher concentrations of MBB
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